One of the most common complaints I have heard from patients is fatigue: they are tired, sometimes all the time, and sometimes exhausted to the extreme. If you have a problem with chronic fatigue, you could benefit from a new supplement called “Asian Energy Boost”.

Just as the name implies, this supplement was originally an ancient traditional Chinese medicinal formula. They have been found to work at the cellular level to boost your body’s own natural production of ATP. The first agent is from a potent medicinal mushroom called cordyceps, and the other is from a root, ginseng root.

Whatever the source or your fatigue, whether it is mental, emotional, physical, or stress-induced, the combination of these two compound can boost your ATP levels and help you maintain optimal energy over time.

Let’s start with explaining ATP production. Every cell in your body contains tiny components (organelles) called mitochondria. They are the energy producing parts of the cell through a process called the Kreb’s cycle and ATP production. Over time, due simply to the “aging” process, these mitochondria may become damaged or don’t work at maximum efficiency. Thus, many of us get tired easily as we age.

However, because we now have options that will help boost the efficiency of our mitochondria, we can have renewed energy. First, we must make sure you are not suffering from a medical problem. Conditions such as hypothyroidism, low testosterone hormone levels, anemia from low iron or vitamin reserves, chronic fatigue syndrome, adrenal fatigue and fibromyalgia should be evaluated and treated.

But, after these conditions are adequately treated and you still are having fatigue, the next thing is to boost your health and your energy producing mitochondria. There are many ways of doing this. All support the production of ATP in your mitochondria so you have more energy coming from every cell of your body.

One way to do this is with this Asian Energy Boost. Cordyceps enhances your ability to burn fuel more efficiently and store its energy as ATP. Ginseng supports ATP production at a higher level and when oxygen is available.

Cordyceps sinensis is considered one of the most valuable medicinal mushrooms in China due to its rarity and valuable health benefits. New science has uncovered how cordyceps enhances energy level in three ways:

1. By raising ATP levels, even under stressful conditions.

2. By lowering levels of lactic acid, the substance that produces fatigue in over stressed muscles.

3. By increasing insulin sensitivity, forcing your body’s cells to take up and utilize glucose better.

Ginseng (panax ginseng) has been shown to increase ATP production in the mitochondria. It also activates multiple enzymes in the Kreb’s cycle to help utilize the glucose in the presence of oxygen.

They thus enhance both physical and mental energy, and many studies have confirmed these actions. (1-12)

People with depression often complain of lack of energy to do anything. This could be considered more mental fatigue than physical, but just as debilitating. Recent studies have shown that brain cell ATP levels in these individuals is low, which would explain that “blah” feeling and lack of motivation in these people. By restoring ATP levels, the brain is able to function at a higher level and thus, less fatigue. (13)

Another benefit of ginseng is that it improves GABA levels, which is a calming neurotransmitter. (14) It does this by directly increasing your body’s own GABA production, resulting in a more natural sense of calmness and healthier sleep. (13, 14) Other studies have also shown ginseng’s ability to increase cognition (15, 16), and improve one’s working memory along with feelings of calmness. (17)

Unfortunately, normally ginseng is poorly absorbed from the gut. However, advanced formulations of ginseng undergo a natural fermentation process resulting in increased absorption of the active compounds of ginseng by more than 15-fold. (18)

A second method to boost ATP production is to increase the concentration of cofactors and building blocks necessary to produce ATP. High dose vitamins, especially B vitamins can be infused and substrates of NAD and AMP can be injected to boost your mitochondrial energy production.

In summary, both cordyceps and ginseng have hundreds of years’ worth of proven energy-boosting benefits without addictive or toxic potential. Both supplements are now known to act by raising ATP levels, making more energy available to brain, muscle, and other vital organs, restoring more youthful energy levels. IV Therapy is another promising option for those who have persistent fatigue.

If you’re interested in trying “Asian Energy Boost” or IV Therapy, they are available at our office. To schedule an appointment for further evaluation and to learn about our other options to help boost your energy and make you feel younger again, call 817-399-8783.

References:

  1. Manabe N, Azuma Y, Sugimoto M, et al. Effects of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism and blood flow in dietary hypoferric anaemic mice. Br J Nutr. 2000 Feb;83(2):197-204.
  2. Li XT, Chen R, Jin LM, Chen HY. Regulation on energy metabolism and protection on mitochondria of Panax ginseng polysaccharide. Am J Chin Med. 2009;37(6):1139-52.
  3. Yan W, Li T, Lao J, Song B, Shen Y. Anti-fatigue property of Cordyceps guangdongensis and the underlying mechanisms. Pharm Biol. 2013 May;51(5):614-20.
  4. Kumar R, Negi PS, Singh B, Ilavazhagan G, Bhargava K, Sethy NK. Cordyceps sinensis promotes exercise endurance capacity of rats by activating skeletal muscle metabolic regulators. J Ethnopharmacol. 2011 Jun 14;136(1):260-6.
  5. Koh JH, Kim KM, Kim JM, Song JC, Suh HJ. Antifatigue and antistress effect of the hot-water fraction from mycelia of Cordyceps sinensis. Biol Pharm Bull. 2003 May;26(5):691-4.
  6. Oliynyk S, Oh S. Actoprotective effect of ginseng: improving mental and physical performance. J Ginseng Res. 2013 Apr;37(2):144-66.
  7. Xie J, Shao J, Lu Y, et al. Separation of ginseng active ingredients and their roles in cancer metastasis supplementary therapy. Curr Drug Metab. 2013 Jun 1;14(5):616-23.
  8. Lee NH, Yoo SR, Kim HG, Cho JH, Son CG. Safety and tolerability of Panax ginseng root extract: a randomized, placebo-controlled, clinical trial in healthy Korean volunteers. J Altern Complement Med. 2012 Nov;18(11):1061-9.
  9. Choi JY, Woo TS, Yoon SY, et al. Red ginseng supplementation more effectively alleviates psychological than physical fatigue. J Ginseng Res. 2011 Sep;35(3):331-8.
  10. Wang LC, Lee TF. Effect of ginseng saponins on exercise performance in non-trained rats. Planta Med. 1998 Mar;64(2):130-3.
  11. Tadano T, Nakagawasai O, Niijima F, Tan-No K, Kisara K. The effects of traditional tonics on fatigue in mice differ from those of the antidepressant imipramine: a pharmacological and behavioral study. Am J Chin Med. 2000;28(1):97-104.
  12. Zhao W, Zhang X, Wang W, Zhang L. Experimental study for the anti-fatigue effect of ginseng general ginsenosides P.E. in vivo. Wei Sheng Yan Jiu. 2009 Mar;38(2):184-7.
  13. Cao X, Li LP, Wang Q, et al. Astrocyte-derived ATP modulates depressive-like behaviors. Nat Med. 2013 Jun;19(6):773-7.
  14. Kitaoka K, Uchida K, Okamoto N, et al. Fermented ginseng improves the first-night effect in humans. Sleep. 2009 Mar;32(3):413-21.
  15. Available at: http://pharmacologycorner.com/animation-benzodiazepines-diazepam-lorazepam-alprazolam/. Accessed August 27, 2013.
  16. Reay JL, Kennedy DO, Scholey AB. Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. J Psychopharmacol. 2005 Jul;19(4):357-65.
  17. Reay JL, Kennedy DO, Scholey AB. Effects of Panax ginseng, consumed with and without glucose, on blood glucose levels and cognitive performance during sustained ‘mentally demanding’ tasks. J Psychopharmacol. 2006 Nov;20(6):771-81.
  18. Jin H, Seo JH, Uhm YK, Jung CY, Lee SK, Yim SV. Pharmacokinetic comparison of ginsenoside metabolite IH-901 from fermented and non-fermented ginseng in healthy Korean volunteers. J Ethnopharmacol. 2012 Jan 31;139(2):664-7.