Testosterone therapy could help you live longer with better quality of life. That is a promise based on the many effect’s testosterone induces in your body. It’s not just a “sex hormone”. It actually should be a “total body hormone” because it affects every cell in your body. Essentially, your metabolism relies on testosterone to keep it revved up.

 

It is an anti-aging hormone because it can prevent or reverse some of the changes that you see as you age. Some age-related changes include loss of lean body mass, lower energy levels, less strength, poor stamina, unexplained depression, decrease in sexual drive, and decrease in performance. Testosterone improves the energy metabolism within your cells acting like a cellular energizer.

 

In addition, degenerative diseases of aging may be directly related to testosterone deficiency as you grow older. Giving testosterone can decrease your risk of developing heart disease, stroke, diabetes, arthritis, osteoporosis, and hypertension.

 

Testosterone is good for the heart. It protects it and improves its function. There are more testosterone receptors in your heart than any other muscle. Testosterone levels correlate better with heart disease than cholesterol levels. Your heart functions better when you have higher levels of testosterone.[1]The lower your level of testosterone, the more likely you’re going to have heart disease. People with heart disease have a significantly lower level of testosterone than healthy people.[2]

 

In a large study of 4,000 men, those who had higher levels of testosterone in their blood were 71% less likely to die from heart disease than those who had the least.[3]Higher levels of testosterone also improve the health and functioning of the inner lining of your blood vessels, or what we call the endothelium.[4]It also increases blood flow to the heart, which increases transport of oxygen and nutrients to the heart to make it healthier.[5]

 

Another action of testosterone on your arteries is that it appears to prevent blood clot formation within the arteries.[6]This thinning of the blood helps decrease your risk of developing blood clots, which could cause pulmonary emboli or stroke. Testosterone therapy decreases the risk of development of heart attacks by 7-fold and the risk of stroke by 9-fold.[7]Thus, it provides a protective effect against MI’s (heart attacks) and strokes.

 

There are many myths about testosterone therapy. One is that it causes prostate cancer. In reality, lower levels of testosterone are more associated with prostate cancer than higher levels, and it’s more aggressive with low levels.[8],[9],[10]  The risk of developing prostate cancer does not increase with higher levels of testosterone.

 

But testosterone therapy can improve your health. Testosterone deficiencies are associated with higher risks of diabetes[11], heart disease[12], Alzheimer’s disease[13], cognitive decline[14],[15], frailty[16], loss of bone structure, and cancer. In addition, inflammation with low levels and inflammation is thought to be a significant root cause why all these problems happen. Testosterone therapy can improve them, and it has been shown to improve Alzheimer’s symptoms.[17]And there’s no increased risk of stroke with testosterone therapy.[18]

 

Testosterone treatment with adequate monitoring may be safer than no treatment.[19]Mortality, or death, over time is markedly decreased when you have adequate levels of testosterone.  Higher levels of testosterone equate to low mortality from cardiovascular disease and cancer while low levels predict higher incidence of these conditions. .[20]

 

Testosterone therapy also can improve your quality of life. As you get older, your testosterone levels drop resulting in symptoms of testosterone deficiency. These include fatigue, tiredness, mood changes[21], depression, irritability, reduced libido and potency[22]. The latter includes decreases in desire, fantasies, morning erections, erectile tension, and intensity of orgasms. Testosterone therapy reverses all these problems.

In conclusion, get your testosterone level evaluated whether you are a man or a woman. If found to be low, embrace testosterone therapy for better health and to feel better too.

 


[1]Jin Q, Lou Y, Chen H, Li T, Bao X, Liu Q, He X. “Lower free testosterone level is correlated with left ventricular diastolic dysfunction in asymptomatic middle-aged men with type 2 diabetes mellitus.” Int J Clin Pract. 2014.

[2]“Low testosterone levels are associated with CVD risk.” Nat Rev Endocrinol. 2011 Oct 21;7(11):632.

[3]“Low testosterone levels are associated with CVD risk.” Nat Rev Endocrinol. 2011 Oct 21;7(11):632.

[4]Ong PSL, Patrizi G, Chong WCF, Webb CM, Haywar’d CS, Collins P. “Testosterone enhances flow mediated brachial artery reactivity in men with coronary artery disease.” Am J Cardiol. 2000. 85:14–17.

[5]Webb CM, McNeill JG, Hayward CS, Zeegler D, Collins P. “Effect of testosterone on coronary vasomotor regulation in men with coronary heart disease.” Circulation. 1999. 100:1690-1693.

[6]Webb CM, McNeill JG, Hayward CS, Zeegler D, Collins P. “Effect of testosterone on coronary vasomotor regulation in men with coronary heart disease.” Circulation. 1999. 100:1690-1693.

[7]Tan RS, Cook K, Reilly WR. Testosterone therapy is not associated with MI or strokes. Abstract 1353. Presented at American Association Clinical Endocrinology 23rd Annual Scientific Meeting May 16th, 2014

 

[8]Shores, MM, et al., Testosterone Treatment and Mortality in Men with Low Testosterone Levels, J Clin Endocrinol Metab. 2012, April

[9]Endogenous Sex Hormones and Prostate Cancer: A Collaborative Analysis of 18 Prospective Studies Endogenous Hormones and Prostate Cancer Collaborative Group . J Natl Cancer Inst 2008 100: 170-183

[10]Gould DC, Kirby RS. Testosterone replacement therapy for late onset hypogonadism: what is the risk of inducing

prostate cancer? Prostate Cancer Prostatic Dis. 2006;9(1):14-8.

[11]Kim C, et al., Endogenous sex hormones, metabolic syndrome, and diabetes in men and women. Curr Cardiol Rep. 2014 Apr;16(4):467

[12]Turhan S et al. The association between androgen levels and premature coronary artery disease in men. Coron Artery Dis. 2007 May;18(3):159-62.

[13]Gouras, GK, et al., Testosterone reduces neuronal secretion of Alzheimer’s beta-amyloid peptides. Proc Natl Acad Sci U S A, 2000, Feb 1;97(3):1202-5

[14]Alexander GM, Swerdloff RS, Wang C, et al., Androgen-behavior correlations in hypogonadal men and eugonadal men. II. Cognitive abilities. Hormones and Behavior 1998; 33(2):85-94

[15]Barrett-Connor E et al. Endogenous sex hormones and cognitive function in older men. J Clin Endocrinol Metab 1999 Oct;84(10):3681

[16]Hyde, Zoe et al. Low Free Testosterone Predicts Frailty in Older Men: The Health in Men Study. JCEM Vol 95, No 7.p 3165-3172.

[17]Tan RS A pilot study on the effects of testosterone in hypogonadal aging male patients with Alzheimer’s disease. Aging Male. 2003 Mar;6 (1):13-7

[18]Glueck, C et al. Testosterone, Thrombophilia, and Thrombosis Clin Appl Thromb Hemost.23 April 201

[19]Feneley MR et al. Is testosterone treatment good for the Prostate? Study of safety during long term treatment. Journal of Sex Med 2012; June 6

[20]Khaw KT, et al., Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men. Circulation. 2007;116:2694-2701

[21]Burris A, et al., A long-term, prospective study of the physiologic and behavioral effects of hormone replacement in untreated hypogonadal men. J Androl 1992 Jul-Aug;13(4):297-304

[22]Caretta N et al. Erectile dysfunction in aging men: testosterone role in therapeutic protocols. J Endocrinol Invest. 2005;28 (11 Suppl Proceedings):108-11